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PubMed COVID-19 Clinical Care

2061 - 2070 of 6585 results found

A controlled effects approach to assessing immune correlates of protection

Date
Wednesday, October 18, 2023 - 4:00 AM
Description
An immune correlate of risk (CoR) is an immunologic biomarker in vaccine recipients associated with an infectious disease clinical endpoint. An immune correlate of protection (CoP) is a CoR that can be used to reliably predict vaccine efficacy (VE)

A fairness assessment of mobility-based COVID-19 case prediction models

Date
Wednesday, October 18, 2023 - 4:00 AM
Description
In light of the outbreak of COVID-19, analyzing and measuring human mobility has become increasingly important. A wide range of studies have explored spatiotemporal trends over time, examined associations with other variables, evaluated non

Adaptive designs in critical care trials: a simulation study

Date
Wednesday, October 18, 2023 - 4:00 AM
Description
CONCLUSIONS: This study confirms the right adaptive design can reach the same conclusion as a fixed design with a much-reduced sample size. The efficiency gain associated with an increased number of interims is highly relevant to late-phase critical