PubMed COVID-19 Clinical Care
2281 - 2290 of 5828 results found
Targeting SARS-CoV-2 Macrodomain-1 to Restore the Innate Immune Response Using In Silico Screening of Medicinal Compounds and Free Energy Calculation Approaches
Description
Among the different drug targets of SARS-CoV-2, a multi-domain protein known as NSP3 is a critical element of the translational and replication machinery. The macrodomain-I, in particular, has been reported to have an essential role in the viral
The COVID-19 and chloroquine infodemic: Cross-sectional observational study of content analysis on YouTube
Description
The objective of this study is to evaluate the association between quality and features related to internet users of the most viewed YouTube videos about COVID-19 and chloroquine, during the first wave of the pandemic. We conducted a cross-sectional
The association of upper respiratory infections with neuro-radiological course and attack rate of multiple sclerosis: Results from a large prospective cohort
Description
CONCLUSION: COVID-19 has been shown to increase the risk of MS exacerbations, like other viral URIs.
The current state of Carceral health data: an analysis of "Listening Sessions" with stakeholders
Description
CONCLUSIONS: To tackle these issues of transparency and availability, the authors believe that an independent oversight body could be instrumental to ensuring accurate and timely data collection and reporting. As many participants turned to creating
The association between nirmatrelvir plus ritonavir and the outcomes of nonhospitalized obese patients with COVID-19
Description
CONCLUSION: NMV-r can be associated with a reducing the risk of all-cause ED visits, hospitalization or death for nonhospitalized obese patients with COVID-19. Accordingly, our findings support the use of NMV-r in obese patients.
Twenty-eight-day mortality among patients with severe or critical COVID-19 in Hong Kong during the early stages of the pandemic
Description
CONCLUSION: The 28-day mortality rate among patients with severe or critical COVID-19 in Hong Kong was 12.0%. Older age, history of stroke, use of renal replacement therapy, and shorter duration of lopinavir-ritonavir treatment were independent
The COVID-19 pandemic's impact on sleep medicine fellowship telemedicine training: a follow-up survey of program directors
Description
CONCLUSIONS: Sleep telemedicine utilization during fellowship training was markedly higher on this 2022 survey (97.5%) compared to a similar 2019 survey (33.3%), and most PDs agreed a standardized curriculum could be useful. However, relatively few
Therapeutic management of in-stent thrombosis after thoracic endovascular aortic repair for blunt thoracic aortic injury in a coronavirus disease 2019 patient
Description
A 27-year-old man underwent thoracic endovascular aortic repair for blunt thoracic aortic injury. Fourteen months later, he presented with intermittent paraplegia, congestive heart failure, and a decline of kidney function as a result of high-grade
The Effect of Select SARS-CoV-2 N-Linked Glycan and Variant of Concern Spike Protein Mutations on C-Type Lectin-Receptor-Mediated Infection
Description
The SARS-CoV-2 virion has shown remarkable resilience, capable of mutating to escape immune detection and re-establishing infectious capabilities despite new vaccine rollouts. Therefore, there is a critical need to identify relatively immutable
