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PubMed COVID-19 Clinical Care

24371 - 24380 of 57555 results found

Bisulfite and Nanopore Sequencing for Pseudouridine in RNA

Date
Wednesday, September 13, 2023 - 4:00 AM
Description
ConspectusNucleophilic addition of bisulfite to pyrimidine bases has been known for a half century, and the reaction has been in use for at least a quarter of a century for identifying 5-methylcytidine in DNA. This account focuses on the chemistry of

Genetic therapies in cystic fibrosis

Date
Wednesday, September 13, 2023 - 4:00 AM
Description
PURPOSE OF REVIEW: Advances in cystic fibrosis (CF) therapies over the past decade pivotally changed the morbidity and mortality of CF with the advent of cystic fibrosis transmembrane conductance regulator (CFTR) modulators that rescue dysfunctional