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PubMed COVID-19 Clinical Care

35291 - 35300 of 57555 results found

Computational study of the binding orientation and affinity of noncovalent inhibitors of the papain-like protease (PLpro) from SARS-CoV-1 considering the protein flexibility by using molecular dynamics and cross-docking

Date
Monday, July 10, 2023 - 4:00 AM
Description
The papain-like protease (PLpro) from zoonotic coronaviruses (CoVs) has been identified as a target with an essential role in viral respiratory diseases caused by Severe Acute Respiratory Syndrome-associated coronaviruses (SARS-CoVs). The design of

Medicine's Roots: Through the Banyan Trees

Date
Monday, July 10, 2023 - 4:00 AM
Description
Description I started residency before the COVID-19 pandemic, at a time when we were able to see our patient's faces without masks, give reassuring smiles, and sit closely while discussing a difficult diagnosis. Little did I know that in 2019, the