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PubMed COVID-19 Clinical Care

45601 - 45610 of 57555 results found

Protein kinases: drug targets for immunological disorders

Date
Monday, May 15, 2023 - 4:00 AM
Description
Protein kinases play a major role in cellular activation processes, including signal transduction by diverse immunoreceptors. Given their roles in cell growth and death and in the production of inflammatory mediators, targeting kinases has proven to

The battle against fungi- lessons in antifungal stewardship from COVID-19 times: a consensus statement on behalf of the International Society of Antimicrobial Chemotherapy, Alliance for the Prudent Use of Antibiotics, European Society of Clinical Micro...

Date
Monday, May 15, 2023 - 4:00 AM
Description
The COVID-19 pandemic has undoubtedly highlighted the detrimental effect of secondary pathogens in patients with a primary viral insult. In addition to superinfections with bacterial pathogens, invasive fungal infections were increasingly reported

Prioritization of potential causative genes for schizophrenia in placenta

Date
Monday, May 15, 2023 - 4:00 AM
Description
Our earlier work has shown that genomic risk for schizophrenia converges with early life complications in affecting risk for the disorder and sex-biased neurodevelopmental trajectories. Here, we identify specific genes and potential mechanisms that

Synthetic RNA therapeutics in cancer

Date
Monday, May 15, 2023 - 4:00 AM
Description
Recent advances in the RNA delivery system have facilitated the development of a separate field of RNA therapeutics, with modalities including mRNA, miRNA, antisense oligonucleotide (ASO), siRNA, and circular (circRNA) that have been incorporated

An Australian COVID-19 Respiratory Care Unit Experience

Date
Monday, May 15, 2023 - 4:00 AM
Description
CONCLUSIONS: This study demonstrates the feasibility of operating a CRCU within an Australia tertiary healthcare setting. This article is protected by copyright. All rights reserved.