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PubMed COVID-19 Clinical Care

46951 - 46960 of 57555 results found

SARS-CoV-2 Nsp8 induces mitophagy by damaging mitochondria

Date
Monday, May 08, 2023 - 4:00 AM
Description
Autophagy plays an important role in the interaction between viruses and host cells. SARS-CoV-2 infection can disrupt the autophagy process in target cells. However, the precise molecular mechanism is still unknown. In this study, we discovered that

The specialized pro-resolving lipid mediator Protectin D1 affects macrophages differentiation and activity in Adult-onset Still's disease and COVID-19, two hyperinflammatory diseases sharing similar transcriptomic profiles

Date
Monday, May 08, 2023 - 4:00 AM
Description
INTRODUCTION: COVID-19 and autoinflammatory diseases, such as Adult-onset Still's Disease (AOSD), are characterized by hyperinflammation, in which it is observed massive production and uncontrolled secretion of pro-inflammatory cytokines. The