Loss-of-function mutation in Omicron variants reduces spike protein expression and attenuates SARS-CoV-2 infection
Description
SARS-CoV-2 Omicron variants emerged in 2022 with >30 novel amino acid mutations in the spike protein alone. While most studies focus on the impact of receptor binding domain changes, mutations in the C-terminal of S1 (CTS1), adjacent to the furin
